➀ Researchers developed **PPBC LNPs**, multifunctional nanoparticles integrating photodynamic therapy (PDT), photothermal therapy (PTT), and real-time imaging to combat treatment-resistant bladder cancer;

➁ The nanoparticles demonstrated strong anti-cancer effects by inducing cell death and suppressing autophagy (a resistance mechanism) while enabling high-resolution imaging via photoacoustic and fluorescence modalities;

➂ In vivo trials showed tumor reduction with no toxicity, and scalable microfluidic synthesis supports potential clinical translation for precision medicine.

➀ Developers for medical-device OEMs must balance innovation and safety;

➁ They face numerous challenges in ensuring the safety of medical-device software;

➂ The article discusses how these challenges can be overcome.

➀ The medical device manufacturer Alun Williams highlights a groundbreaking software;

➁ The software is said to have been highly useful in the past 10 years;

➂ No further details about the software are provided in the summary.