➀ Researchers from the Institute for Molecular Science have improved the speed of DNA-nanoparticle motors by optimizing their design, bringing them closer to the speeds of natural motor proteins.

➁ The DNA-nanoparticle motor uses the 'burnt-bridge' Brownian ratchet mechanism, where the degradation of RNA/DNA bonds propels the motor forward.

➂ By increasing the concentration of RNase H, the speed of the motor was significantly enhanced, though it came at the cost of reduced run length and processivity.