➀ The study introduces a biomimetic nanovaccine (AECM@PC7A) that combines IFN-γ-treated tumor cell membranes with a synthetic adjuvant (PC7A) to enhance neoantigen presentation and activate the STING pathway, addressing limitations of conventional cancer vaccines;

➁ In preclinical models, the vaccine triggered robust T-cell responses, reduced tumor growth and metastasis, and demonstrated synergy with immune checkpoint inhibitors, leading to prolonged survival and immune memory;

➂ The platform offers a scalable approach for personalized immunotherapy by leveraging tumor-specific neoantigens and simplified manufacturing processes, showing promise for clinical translation.

➀ Researchers from the University of Connecticut and Eascra Biotech are producing innovative nanomaterials in space to improve treatments for osteoarthritis and cancer.

➁ Janus base nanomaterials (JBNs) are developed to regenerate cartilage and could be used in precision cancer treatment.

➂ The ISS National Lab is used to test the production of JBNs in space, where gravity-driven forces are reduced, leading to better uniformity and patient outcomes.

➀ Researchers from Oregon State University have developed a method to deliver anti-inflammatory drugs across the blood-brain barrier;

➁ This may enable new treatments for diseases such as cancer cachexia, multiple sclerosis, Parkinson’s disease, and Alzheimer's disease;

➂ The delivery system uses specially designed nanoparticles and has been successful in a mouse model.