<p>➀ Researchers from TU Wien have found that nerve stimulation can be more effective when it is synchronized with the body's natural rhythms, such as heart rate and breathing.</p><p>➁ In a pilot study, five individuals were examined, and it was discovered that the timing of the electrical stimulation relative to the heartbeat is crucial.</p><p>➂ When the stimulation signals are set during systole (heart contraction), there is a significant effect compared to stimulation during diastole (heart relaxation).</p>