➀ Researchers at Penn State have developed a method to deliver sound to a specific location without headphones, creating private listening zones.

➁ The technology uses two ultrasonic beams focused by acoustic metasurfaces to form an audible enclave where only the intended listener can hear.

➂ The system has potential applications in enhancing audio privacy in shared spaces and improving in-car audio systems.

➀ Researchers developed lipid nanoparticles (LNPs) to deliver mRNA encoding the KRAS G12D neoantigen and cGAMP to reprogram the liver's immune environment and generate an antitumor response against metastatic pancreatic cancer.

➁ The LNPs successfully activated the type I interferon pathway, leading to the generation of CD8+ cytotoxic T cells capable of recognizing and attacking metastatic cancer cells.

➂ The study suggests that combining KRAS mRNA with a STING agonist strengthens the immune response against PDAC and offers a more effective approach than traditional immunotherapies.

➀ Ed reflects on the sources of €1trn and his strategy to secure a share of it;

➁ Ed discusses the possibility of the US raising €800 billion for 'ReArm Europe' and €200 billion for 'InvestAI';

➂ Ed's assignment to the EU as 'Digital Envoy' and his plan to spend on meals and indulgences to identify influential figures in the spending of the funds.

➀ A leaker claims Valve is releasing a version of SteamOS for desktop systems, expanding its reach beyond gaming handhelds.

➁ The rumor suggests the release is imminent, with Valve preparing for a general public release.

➂ The move aims to provide gamers with an alternative to Windows, the dominant platform on Steam.

➀ The ASRock PG-1600G Phantom Gaming PSU delivers exceptional electrical and overall performance, making it a reliable choice for high-power builds.

➁ Despite its solid thermal and acoustic performance, the PSU's price raises some concerns.

➂ The PSU's design and internal components, including the 135 mm hydraulic bearing fan and FSP's manufacturing, contribute to its solid performance.

➀ MSI has confirmed that it will not manufacture AMD Radeon 9000-series GPUs using the RDNA 4 architecture.

➁ The decision may be due to MSI's intention to focus on Nvidia GPUs or the lack of profitability in the AMD Radeon 9000-series.

➂ The move could be seen as MSI potentially shifting its focus from AMD to Nvidia, similar to EVGA's strategy.

➀ Nvidia claims to have shipped twice as many 50-series GPUs as 40-Series at launch, but the comparison is misleading;

➁ The first five weeks of Ada only had RTX 4090 cards available, while the 50-series GPUs were launched later;

➂ The availability of RTX 50-series GPUs is scarce, with high prices and supply issues.

➀ A new type of miniaturized pumps and valves using ultra-thin silicon films is presented at the Hannover Messe, developed by researchers at Saarland University. These pumps and valves operate without air pressure, motors, and lubricants, and can be operated in clean rooms. The team demonstrates a prototype of a new vacuum pump that can draw a vacuum up to 300 millibars.

➁ The technology is cost-effective, lightweight, and energy-efficient compared to current methods, with a 400 times lower energy consumption compared to conventional air-driven valves.

➂ The researchers have developed a novel actuator and pump technology that can be used in various applications, including robotic grippers, speakers, smart textiles, and haptic feedback.

➀ A team from Saarland University's Faculty of Engineering and Medicine is developing smart implants at the university and university hospital to monitor and promote healing in body bone fractures.

➁ The robotic implants can stiffen and soften through shape-memory technology, allowing for permanent monitoring of fracture healing.

➂ The research team is miniaturizing the technology for use in market screws as part of an EU project.

➀ Salmon skin or Moire issue in 3D prints is a common problem that affects the appearance and finish of the design;

➁ This issue can be caused by various factors such as stepper motor drivers, 3D printer vibrations, and high printing speeds;

➂ The article provides solutions such as checking 3D printer belts, installing TL smoothers, updating firmware, upgrading stepper motors, and reducing printing speed.

➀ The ASRock B860I Lightning is a budget-friendly Mini-ITX motherboard offering robust power delivery and a variety of features for around $220.

➁ It boasts a PCIe 5.0 M.2 socket, integrated Thunderbolt 4, and improved audio, while still offering Wi-Fi 6E.

➂ Performance was average, but gaming performance was competent with default settings.

➀ The GeForce RTX 5060 and 5060 Ti GPUs from Nvidia are rumored to launch in 10 days, but stock is expected to arrive in April.

➁ The 5060 Ti is expected to come in 8GB and 16GB VRAM configurations, while the RTX 5060 may use the GB206 die.

➂ Concerns about performance due to the limited VRAM and potential lack of stock for the RTX 5060 series.

➀ This study explores the use of cationic fusogenic liposomes for improved drug delivery by fusing directly with cellular membranes;

➁ Researchers varied charge density and lipid composition to assess fusion efficiency and membrane effects;

➂ The study found that liposomes can temporarily modify membrane properties without causing long-term damage to cells, suggesting their potential for therapeutic applications.