➀ Researchers at the University of Ottawa have developed a new contrast agent for IV-OCT, using gold superclusters (AuSC) to enhance imaging clarity. ➁ The team coated the AuSC with a special polymer for stability and targeted imaging. ➂ The new agent, AuSC@(13FS)2, binds to P-selectin and improves IV-OCT imaging, potentially leading to personalized heart disease treatments.