<p>➀ Researchers at the University of Michigan developed nanodiscs to target cholesterol levels in GBM tumors, showing promise in increasing survival rates in treated mice; </p><p>➁ Current treatment limitations for GBM include surgery, radiation, and chemotherapy, with no cure available; </p><p>➂ The nanodiscs deliver LXR agonists to increase cellular pumps for cholesterol removal, leading to cancer cell destruction, and stimulate the immune system to target tumors.</p>